HOLY BASIL EXTRACT (OCIMUM SANCTUM)(LEAVES)(2.5% URSOLIC ACID)

Holy Basil, botanically known as Ocimum sanctum or Tulsi, is a revered adaptogenic herb deeply rooted in Ayurvedic medicine for over 3,000 years. Native to the Indian subcontinent and Southeast Asia, this aromatic plant is distinguished by its vibrant green or purple leaves and its profound therapeutic properties. The offered extract is meticulously derived from the leaves of Ocimum sanctum, specifically standardized to contain 2.5% Ursolic Acid. Ursolic acid is a pentacyclic triterpenoid compound recognized as a key bioactive marker for Holy Basil's efficacy. This precise standardization ensures a consistent and potent concentration of active constituents, which is crucial for delivering reliable physiological effects in modern supplement formulations. Traditional uses of Holy Basil span a wide spectrum, encompassing the promotion of overall well-being, enhancement of resilience against environmental stressors, and support for various bodily systems, reflecting its classification as a classic adaptogen. It is important to differentiate this potent medicinal herb from the culinary sweet basil, as their phytochemical profiles and therapeutic applications are distinct.

Holy Basil's comprehensive health benefits are primarily attributed to its rich and complex phytochemistry, which includes a synergistic blend of triterpenes such as ursolic acid, oleanolic acid, and rosmarinic acid, alongside a diverse array of flavonoids and essential oils like eugenol and carvacrol. Ursolic acid, the primary marker compound in this extract, has been extensively investigated for its anti-inflammatory, antioxidant, and immunomodulatory activities. Scientific research suggests that ursolic acid can influence cytokine pathways and protect cellular structures from oxidative damage, as evidenced by studies demonstrating its free-radical scavenging capabilities. The adaptogenic mechanism of Holy Basil involves modulating the hypothalamic-pituitary-adrenal (HPA) axis, thereby helping to normalize cortisol levels and mitigate the physiological impacts of chronic stress. A study published in the *Journal of Ayurveda and Integrative Medicine* elucidated Tulsi's capacity to significantly reduce stress-induced alterations in various biochemical and physiological parameters, supporting its role in stress resilience. Furthermore, Holy Basil contributes to cognitive function, mood balance, and metabolic health through its interactions with neurotransmitter systems and glucose regulation pathways.

Standardized Holy Basil extract (2.5% Ursolic Acid) is a highly versatile ingredient, ideal for incorporation into various supplement formulations, including capsules, tablets, and powdered drink mixes. Its primary applications are focused on stress relief, mood enhancement, and adaptogenic support, often synergistically combined with other adaptogenic herbs such as Ashwagandha, Rhodiola, or Schisandra. Beyond stress management, it is also effectively utilized in formulations targeting immune system modulation, anti-inflammatory support, and cognitive health. The quality of this extract is paramount, necessitating stringent testing for purity, potency, and the absence of contaminants, in full adherence to current Good Manufacturing Practices (cGMP). The growing body of scientific literature, including human clinical trials, continues to validate its efficacy. For instance, a randomized, double-blind, placebo-controlled study published in *Evidence-Based Complementary and Alternative Medicine* demonstrated a notable reduction in generalized stress symptoms and an improvement in cognitive performance among participants supplementing with Holy Basil extract. This robust scientific validation, combined with its long history of safe traditional use, firmly establishes Holy Basil extract as a premium, multi-faceted botanical ingredient for health and wellness products.